This work extends the generalized plasticity model for structural metals under cyclic loading proposed by Lubliner et al. (1993, “A New Model of Generalized Plasticity and its Numerical Implementation,” Int. J. Solids Struct., 22, pp. 3171–3184) to incorporate temperature-dependence into the elastic-plastic response. Proposed flow equations satisfy the Clausius–Duhem inequality through a thermodynamically consistent energy functional and retain key aspects of conventional plasticity models: Mises yield surface, normal plastic flow, and additive decomposition of strain. Uniaxial specialization of the 3D rate equations leads to a simple graphical method to estimate model properties. The 3D integration scheme based on backward Euler discretization leads to a scalar quadratic expression to determine the plastic strain rate multiplier and has a symmetric algorithmic tangent matrix. Both properties of the integration lead to a computationally efficient implementation especially suited to large-scale, finite element analyses. In comparison studies using experimental data from a Cottrell–Stokes test, the modified rate equations for the generalized plasticity model capture a thermally activated increase in the flow stress.