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Keywords: brain
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Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2020, 142(7): 071005.
Paper No: BIO-19-1033
Published Online: March 4, 2020
..., a reliable method for the quantification of the anisotropic mechanical properties of human white matter is currently lacking, despite the potential to illuminate the pathophysiology behind neurological disorders and traumatic brain injury. In this study, we examine the use of multiple excitations in MRE...
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2019, 141(3): 031001.
Paper No: BIO-17-1558
Published Online: January 18, 2019
... studies have investigated the biochemical and genetic aspects of ASD, whether and how mechanical characteristics of the autistic brain can modulate neuronal connectivity and cognition in ASD are unknown. Previously, it has been shown that ASD brains are characterized by abnormal white matter...
Includes: Supplementary data
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2011, 133(7): 071009.
Published Online: July 29, 2011
...Benjamin S. Elkin; Ashok Ilankova; Barclay Morrison, III Stress relaxation tests using a custom designed microindentation device were performed on ten anatomic regions of fresh porcine brain (postmortem time <3 h). Using linear viscoelastic theory, a Prony series representation was used...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. April 2011, 133(4): 041006.
Published Online: March 15, 2011
... of deformation. We demonstrate the use of this methodology by determining the minimal rheological arrangement, constitutive relationships, and model parameters for the structural response of various soft tissues, including ex vivo perfused porcine liver in indentation, ex vivo porcine brain cortical tissue...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2011, 133(2): 021002.
Published Online: January 24, 2011
...Guanglei Li; Bingmei M. Fu The endothelial surface glycocalyx layer (SGL) and the basement membrane (BM) are two important components of the blood-brain barrier (BBB). They provide large resistance to solute transport across the BBB in addition to the tight junctions in the cleft between adjacent...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2010, 132(10): 101004.
Published Online: October 1, 2010
...Andrew K. Knutsen; Yulin V. Chang; Cindy M. Grimm; Ly Phan; Larry A. Taber; Philip V. Bayly Folding of the cerebral cortex is a critical phase of brain development in higher mammals but the biomechanics of folding remain incompletely understood. During folding, the growth of the cortical surface...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2010, 132(9): 091009.
Published Online: August 26, 2010
... of interest, and acceptable magnitude of error when selecting the vascular domain will increase reliability of the results while decreasing computational time. 01 06 2009 16 02 2010 22 02 2010 26 08 2010 26 08 2010 blood vessels brain computational fluid dynamics diseases...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. July 2010, 132(7): 071013.
Published Online: June 2, 2010
...Gang Xu; Andrew K. Knutsen; Krikor Dikranian; Christopher D. Kroenke; Philip V. Bayly; Larry A. Taber During human brain development, the cerebral cortex undergoes substantial folding, leading to its characteristic highly convoluted form. Folding is necessary to accommodate the expansion...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2010, 132(1): 011010.
Published Online: December 18, 2009
...Benjamin S. Elkin; Ashok Ilankovan; Barclay Morrison, III Age-dependent outcomes following traumatic brain injury motivate the study of brain injury biomechanics in experimental animal models at different stages of development. Finite element models of the rat brain are used to better understand...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2010, 132(1): 011005.
Published Online: December 9, 2009
...Gang Xu; Philip S. Kemp; Joyce A. Hwu; Adam M. Beagley; Philip V. Bayly; Larry A. Taber Mechanical forces play an important role during brain development. In the early embryo, the anterior end of the neural tube enlarges and differentiates into the major brain subdivisions, including three...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2009, 131(11): 111010.
Published Online: October 26, 2009
... than that of interface friction. Taken together, these findings demonstrate the advantages of flash freezing in biomechanical studies of spine cord tissue. 02 12 2008 11 05 2009 01 09 2009 26 10 2009 biological tissues biomechanics biothermics brain finite element...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2009, 131(11): 111003.
Published Online: October 16, 2009
... ( 10 ) and also potentially vertebral strength. 03 09 2008 20 05 2009 16 10 2009 biomechanics bone brain finite element analysis Osteoporotic vertebral compression fractures are estimated to affect 700,000 individuals yearly in the United States alone ( 1...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101013.
Published Online: September 17, 2009
... . Schematic of the reference configurations for the dual mechanism constitutive model with relevant kinematic variables drawn biomechanics blood vessels brain diseases failure analysis fatigue finite element analysis haemodynamics proteins cerebral arteries...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101010.
Published Online: September 4, 2009
... 2008 08 07 2009 04 09 2009 anisotropic media biomechanics blood vessels brain diseases elasticity proteins shear strength aneurysm artery cerebral collagen membrane saccular Saccular cerebral aneurysms are detected in less than 5% of the human population...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101003.
Published Online: September 1, 2009
... vessels brain cellular biophysics diseases haemodynamics neurophysiology physiological models shear flow Recall that a small initial dilatation is generated by prescribing a degradation of elastin in a localized region of the tissue. The artery is then allowed to stabilize until it achieves...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2009, 131(9): 091004.
Published Online: August 4, 2009
... No. DBI-0442269. Wardlaw , J. M. , and White , P. M. , 2000 , “ The Detection and Management of Unruptured Intracranial Aneurysms ,” Brain 0006-8950 , 123 , pp. 205 – 221 . 10.1093/brain/123.2.205 Kassell , N. F. , Torner , J. C. , Haley , E. C. , and Adams...
Journal Articles
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074002.
Published Online: July 27, 2009
...Kazuto Masamoto; Kazuo Tanishita Oxygen is essential to maintaining normal brain function. A large body of evidence suggests that the partial pressure of oxygen ( p O 2 ) in brain tissue is physiologically maintained within a narrow range in accordance with region-specific brain activity. Since...