... to maintain mechanical tissue homeostasis, the response of aged tendons to altered levels of mechanical loading has not yet been studied. To address this question, we subjected young and aged murine flexor tendon explants to various levels of in vitro tensile strain. We first compared the effect of static...

... significantly increased with increased loading rate, while failure strain significantly decreased with increased loading rate. The failure stress and failure strain for all liver parenchyma specimens ranged from −38.9 kPa to −145.9 kPa and from −0.48 strain to −1.15 strain, respectively. Overall, this study...

... pressure (LVP) as a reliable gating signal. By taking the time derivative of the LVP (dP/dt), we were able to start imaging at both end-diastole for systolic phase images, and end-systole for diastolic phase images. We also used MR tissue tagging to calculate 3D strain information during diastole. Using...

... world crash data reported in the Crash Injury Research and Engineering Network (CIREN) database, finite element (FE) models of vehicles, and the Wayne State Human Body Model - II (WSHBM). For the eight CIREN cases reconstructed, the high strain regions in the aorta closely matched with the autopsy data...

...Habiba Bougherara; Ehsan Rahim; Suraj Shah; Anton Dubov; Emil H. Schemitsch; Rad Zdero With the resurgence of composite materials in orthopaedic applications, a rigorous assessment of stress is needed to predict any failure of bone-implant systems. For current biomechanics research, strain gage...

... on the infraspinatus tendon is unknown. Since we have established a relationship between strain in the supraspinatus and infraspinatus tendons the success of a supraspinatus tendon repair depends on its effect on the loading environment in the infraspinatus tendon. More specifically, the effect of transosseous...

..., the anterior deep region, the posterior superficial region, and the posterior deep region of the AF. where ℓ is the current length of the tissue sample and L is the original length of the tissue sample. Stretch ratios were calculated rather than strain as the deformations observed by AF tissue...

... apply uniaxial stretch from both ends simultaneously. Using the biostretch apparatus, the distributions of the strain on the Gelfoam® and GE RTV 6166 silicon scaffolds are quantitatively analyzed. In this study, a uniaxial biostretch apparatus has been developed to culture engineered tissue patches...

...Chong Wang; Ghassan S. Kassab The stress distribution in the vessel wall has important bearing on vascular function including intima, media, and adventitia. The residual strain in the vessel wall has been thought to largely normalize the transmural stress distribution with slightly higher values...

.... The simulation of wall stress was based on transmural measurements of strain and material properties of coronary arteries in reference to the zero-stress state. A one-layer model with material constants of the intact vessel was used to calculate the circumferential stress distribution. A sensitivity analysis...

...Michael R. Hardisty; Cari M. Whyne Quantification of bone strain can be used to better understand fracture risk, bone healing, and bone turnover. The objective of this work was to develop and validate an intensity matching image registration method to accurately measure and spatially resolve strain...

...Benjamen A. Filas; Andrew K. Knutsen; Philip V. Bayly; Larry A. Taber During morphogenesis, epithelia (cell sheets) undergo complex deformations as they stretch, bend, and twist to form the embryo. Often these changes in shape create multivalued surfaces that can be problematic for strain...

... ligament (MCL) by evaluating the effects of ACL deficiency on local MCL strain while simultaneously measuring joint kinematics under specific loading scenarios. A structural testing machine applied anterior translation and valgus rotation (limits 100 N and 10 N m , respectively) to the tibia of ten human...

... in a small aneurysm to as high as 1.06 MPa in a giant aneurysm. The patterns of distribution of stress, strain, and surface curvature were found to be similar. Sensitivity analyses showed that the computed stress is mesh independent and not very sensitive to reasonable perturbations in model parameters...

...A. Ramos; F. Fonseca; J. A. Simões The determination of biomechanical force systems of implanted femurs to obtain adequate strain measurements has been neglected in many published studies. Due to geometric alterations induced by surgery and those inherent to the design of the prosthesis...

...Alexander I. Veress; Grant T. Gullberg; Jeffrey A. Weiss The assessment of regional heart wall motion (local strain) can localize ischemic myocardial disease, evaluate myocardial viability, and identify impaired cardiac function due to hypertrophic or dilated cardiomyopathies. The objectives...

...Wei Zhang; Carly Herrera; Satya N. Atluri; Ghassan S. Kassab There is no doubt that atherosclerosis is one of the most important health problems in the Western Societies. It is well accepted that atherosclerosis is associated with abnormal stress and strain conditions. A compelling observation...

... must be performed to correlate material points between image pairs. The objective of this study was to determine the efficacy of an image registration technique termed Warping to determine strains in plaques and coronary arteries from paired IVUS images representing two different states of deformation...