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Journal Articles

Methodology for Computational Fluid Dynamic Validation for Medical Use: Application to Intracranial Aneurysm

Nikhil Paliwal, Robert J. Damiano, Nicole A. Varble, Vincent M. Tutino, Zhongwang Dou, Adnan H. Siddiqui, Hui Meng
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2017, 139(12): 121004.
Paper No: BIO-17-1030
https://doi.org/10.1115/1.4037792
Published Online: September 28, 2017
View Article titled, Methodology for Computational Fluid Dynamic Validation for Medical Use: Application to Intracranial Aneurysm
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Topics: Computational fluid dynamics, Errors, Flow (Dynamics), Uncertainty, Simulation, Aneurysms
Includes: Supplementary data
Journal Articles

Flow Instability Detected by High-Resolution Computational Fluid Dynamics in Fifty-Six Middle Cerebral Artery Aneurysms

Nicole Varble, Jianping Xiang, Ning Lin, Elad Levy, Hui Meng
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2016, 138(6): 061009.
Paper No: BIO-15-1455
https://doi.org/10.1115/1.4033477
Published Online: May 10, 2016
View Article titled, Flow Instability Detected by High-Resolution Computational Fluid Dynamics in Fifty-Six Middle Cerebral Artery Aneurysms
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Topics: Aneurysms, Flow (Dynamics), Fluctuations (Physics), Resolution (Optics), Inflow, Flow instability, Computational fluid dynamics
Journal Articles

The Computational Fluid Dynamics Rupture Challenge 2013—Phase II: Variability of Hemodynamic Simulations in Two Intracranial Aneurysms

Philipp Berg, Christoph Roloff, Oliver Beuing, Samuel Voss, Shin-Ichiro Sugiyama, Nicolas Aristokleous, Andreas S. Anayiotos, Neil Ashton, Alistair Revell, Neil W. Bressloff, Alistair G. Brown, Bong Jae Chung, Juan R. Cebral, Gabriele Copelli, Wenyu Fu, Aike Qiao, Arjan J. Geers, Simona Hodis, Dan Dragomir-Daescu, Emily Nordahl, Yildirim Bora Suzen, Muhammad Owais Khan, Kristian Valen-Sendstad, Kenichi Kono, Prahlad G. Menon, Priti G. Albal, Otto Mierka, Raphael Münster, Hernán G. Morales, Odile Bonnefous, Jan Osman, Leonid Goubergrits, Jordi Pallares, Salvatore Cito, Alberto Passalacqua, Senol Piskin, Kerem Pekkan, Susana Ramalho, Nelson Marques, Stéphane Sanchi, Kristopher R. Schumacher, Jess Sturgeon, Helena Švihlová, Jaroslav Hron, Gabriel Usera, Mariana Mendina, Jianping Xiang, Hui Meng, David A. Steinman, Gábor Janiga
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2015, 137(12): 121008.
Paper No: BIO-14-1543
https://doi.org/10.1115/1.4031794
Published Online: November 5, 2015
View Article titled, The Computational Fluid Dynamics Rupture Challenge 2013—Phase II: Variability of Hemodynamic Simulations in Two Intracranial Aneurysms
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Topics: Aneurysms, Computational fluid dynamics, Engineering simulation, Flow (Dynamics), Hemodynamics, Rupture, Simulation, Pressure, Cycles, Computation
Proceedings Papers

Method of Extrapolating Low Speed Compressor Curves Based on Improved Similarity Laws

Zhitao Wang, Yi-Guang Li, Hui Meng, Shuying Li, Ningbo Zhao
Proc. ASME. GT2015, Volume 3: Coal, Biomass and Alternative Fuels; Cycle Innovations; Electric Power; Industrial and Cogeneration, V003T20A017, June 15–19, 2015
Publisher: American Society of Mechanical Engineers
Paper No: GT2015-44108
https://doi.org/10.1115/GT2015-44108
View Paper titled, Method of Extrapolating Low Speed Compressor Curves Based on Improved Similarity Laws
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Topics: Compressors, Gas turbines, Compressibility, Engineering simulation, Fluids, Incompressible fluids, Pumps, Simulation
Proceedings Papers

Vortex Generation in Two Intracranial Aneurysms

Hafez Asgharzadeh, Iman Borazjani, Jianping Xiang, Hui Meng
Proc. ASME. IDETC-CIE2014, Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, V003T12A010, August 17–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: DETC2014-35703
https://doi.org/10.1115/DETC2014-35703
View Paper titled, Vortex Generation in Two Intracranial Aneurysms
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Topics: Aneurysms, Vortices, Computer simulation, Domes (Structural elements), Flow (Dynamics), Geometry, Hemodynamics, Shapes, Transportation systems
Proceedings Papers

Fast Virtual Stenting With Vessel-Specific Initialization and Collision Detection

Nikhil Paliwal, Hongyu Yu, Robert Damiano, Jianping Xiang, Xinjian Yang, Adnan Siddiqui, Haiyun Li, Hui Meng
Proc. ASME. IDETC-CIE2014, Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, V003T12A014, August 17–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: DETC2014-35712
https://doi.org/10.1115/DETC2014-35712
View Paper titled, Fast Virtual Stenting With Vessel-Specific Initialization and Collision Detection
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Topics: Collisions (Physics), Vessels, Stents, Aneurysms, Blood vessels, Decision making, Hemodynamics, Surgery
Proceedings Papers

Vortex Dynamics of Ruptured and Unruptured Intracranial Aneurysms

Nicole Varble, Gabriel Trylesinski, Jianping Xiang, Hui Meng
Proc. ASME. IDETC-CIE2014, Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, V003T12A015, August 17–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: DETC2014-35713
https://doi.org/10.1115/DETC2014-35713
View Paper titled, Vortex Dynamics of Ruptured and Unruptured Intracranial Aneurysms
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Topics: Aneurysms, Dynamics (Mechanics), Vortices, Brain, Computational fluid dynamics, Engineering simulation, Fluids, Imaging, Rupture, Simulation
Proceedings Papers

Computational Hemodynamic Evaluation of Two Clinical Flow-Diverter Treatment Strategies: Overlapping Stents vs. Dense Compaction of a Single Stent

Robert Damiano, Jianping Xiang, Adnan Siddiqui, Hui Meng
Proc. ASME. IDETC-CIE2014, Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, V003T12A016, August 17–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: DETC2014-35716
https://doi.org/10.1115/DETC2014-35716
View Paper titled, Computational Hemodynamic Evaluation of Two Clinical Flow-Diverter Treatment Strategies: Overlapping Stents vs. Dense Compaction of a Single Stent
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Topics: Compacting, Flow (Dynamics), Hemodynamics, Stents, Aneurysms, Computational fluid dynamics, Finite element methods, Metals
Proceedings Papers

A New Virtual Coiling Method and its Use in Evaluation of Combining Coiling and Flow-Diversion Treatment in a Patient-Specific Aneurysm

Robert Damiano, Jianping Xiang, Elad Levy, Hui Meng
Proc. ASME. IDETC-CIE2014, Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices, V003T12A017, August 17–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: DETC2014-35718
https://doi.org/10.1115/DETC2014-35718
View Paper titled, A New Virtual Coiling Method and its Use in Evaluation of Combining Coiling and Flow-Diversion Treatment in a Patient-Specific Aneurysm
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Topics: Aneurysms, Flow (Dynamics), Packing (Shipments), Packings (Cushioning), Finite element methods, Hemodynamics, Carotid arteries, Density, Fluctuations (Physics), Thrombosis
Proceedings Papers

Comparison of Flow Diverter Deployment Strategies for Cerebral Aneurysm Treatment: Evaluation of Hemodynamic Modifications

Robert Damiano, Chris Martensen, Ding Ma, Jianping Xiang, Adnan Siddiqui, Hui Meng
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT57A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14814
https://doi.org/10.1115/SBC2013-14814
View Paper titled, Comparison of Flow Diverter Deployment Strategies for Cerebral Aneurysm Treatment: Evaluation of Hemodynamic Modifications
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Topics: Aneurysms, Flow (Dynamics), Hemodynamics, Blood, Geometry, Packing (Shipments), Packings (Cushioning), Performance, Pipelines, Platelets
Proceedings Papers

AView: A Clinical Tool for Hemodynamic and Morphological Analysis of Intracranial Aneurysms

Jianping Xiang, Nicole Varble, Adnan Siddiqui, Luca Antiga, Hui Meng
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT04A028, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14770
https://doi.org/10.1115/SBC2013-14770
View Paper titled, AView: A Clinical Tool for Hemodynamic and Morphological Analysis of Intracranial Aneurysms
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Topics: Aneurysms, Hemodynamics, Rupture, Workflow, Engineering prototypes, Risk, Risk assessment
Proceedings Papers

Intracranial Aneurysm Morphology and Flow Dynamics to Assess Rupture Risk

Jianping Xiang, Markus Tremmel, Ding Ma, J. Mocco, Adnan Siddiqui, Hui Meng
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 521-522, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206394
https://doi.org/10.1115/SBC2009-206394
View Paper titled, Intracranial Aneurysm Morphology and Flow Dynamics to Assess Rupture Risk
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Topics: Aneurysms, Flow (Dynamics), Risk, Rupture, Vessels
Proceedings Papers

High Wall Shear Stress and Positive Wall Shear Stress Gradient Trigger the Initiation of Intracranial Aneurysms

Eleni Metaxa, Markus Tremmel, Jianping Xiang, John Kolega, Max Mandelbaum, Adnan Siddiqui, J. Mocco, Hui Meng
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 523-524, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206395
https://doi.org/10.1115/SBC2009-206395
View Paper titled, High Wall Shear Stress and Positive Wall Shear Stress Gradient Trigger the Initiation of Intracranial Aneurysms
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Topics: Aneurysms, Shear stress, Hemodynamics, Bifurcation, Flow (Dynamics)
Proceedings Papers

CFD Challenge: Solutions Using the Commercial Finite Volume Solver, STAR-CD

Jianping Xiang, Hui Meng
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 153-154, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80860
https://doi.org/10.1115/SBC2012-80860
View Paper titled, CFD Challenge: Solutions Using the Commercial Finite Volume Solver, STAR-CD
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Topics: Computational fluid dynamics, Aneurysms, Engineering simulation, Flow (Dynamics), Simulation, Students
Proceedings Papers

Flow Modification of Cerebral Aneurysm by Flow Diverter (Pipeline) With Different Packing Densities

Jianping Xiang, Ding Ma, Adnan Siddiqui, Hui Meng
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 499-500, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80764
https://doi.org/10.1115/SBC2012-80764
View Paper titled, Flow Modification of Cerebral Aneurysm by Flow Diverter (Pipeline) With Different Packing Densities
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Topics: Aneurysms, Flow (Dynamics), Packing (Shipments), Packings (Cushioning), Pipelines, Blood flow, Catheters, Cavities, Density, Food and Drug Administration
Proceedings Papers

Size Ratio of Intracranial Aneurysms Predicts Rupture-Prone Hemodynamics

Jianping Xiang, Adnan Siddiqui, Sabareesh K. Natarajan, Hui Meng
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 459-460, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53712
https://doi.org/10.1115/SBC2011-53712
View Paper titled, Size Ratio of Intracranial Aneurysms Predicts Rupture-Prone Hemodynamics
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Topics: Aneurysms, Hemodynamics, Rupture, Flow (Dynamics), Geometry, Vessels
Proceedings Papers

Positive and Negative Wall Shear Stress Gradients Have Different Effects on Endothelial Phenotype Under High Wall Shear Stress

Jennifer Dolan, Frasier Sim, Hui Meng, John Kolega
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 137-138, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53490
https://doi.org/10.1115/SBC2011-53490
View Paper titled, Positive and Negative Wall Shear Stress Gradients Have Different Effects on Endothelial Phenotype Under High Wall Shear Stress
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Topics: Shear stress, Aneurysms, Flow (Dynamics), Hemodynamics, Vessels, Bifurcation, Blood vessels
Proceedings Papers

Finite Element Study of Conformity of Flow Diverter With Intracranial Aneurysmal Vasculatures

Ding Ma, Jianping Xiang, Adnan Siddiqui, Sabareesh Natarajan, Hui Meng
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1117-1118, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53772
https://doi.org/10.1115/SBC2011-53772
View Paper titled, Finite Element Study of Conformity of Flow Diverter With Intracranial Aneurysmal Vasculatures
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Topics: Finite element analysis, Flow (Dynamics), Stents, Aneurysms, Finite element methods, Alloys, Blood flow, Cascades (Fluid dynamics), Damage, Endothelial cells
Proceedings Papers

2D and 3D Morphologic Metrics Associated Intracranial Aneurysm Rupture

Ding Ma, Sabareesh K. Natarajan, Jianping Xiang, Adnan Siddiqui, Elad I. Levy, J. Mocco, Hui Meng
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 937-938, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19633
https://doi.org/10.1115/SBC2010-19633
View Paper titled, 2D and 3D Morphologic Metrics Associated Intracranial Aneurysm Rupture
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Topics: Aneurysms, Rupture, Image segmentation, Geometry, Hemodynamics, Imaging, Risk, Vessels
Proceedings Papers

Early Cellular and Molecular Changes During Hemodynamic Initiation of Intracranial Aneurysms in a Rabbit Model

Ling Gao, Max Mandelbaum, Nicholas Liaw, Sabareesh K. Natarajan, J. Mocco, Adnan H. Siddiqui, Hui Meng, John Kolega
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 577-578, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19598
https://doi.org/10.1115/SBC2010-19598
View Paper titled, Early Cellular and Molecular Changes During Hemodynamic Initiation of Intracranial Aneurysms in a Rabbit Model
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Topics: Aneurysms, Hemodynamics, Flow (Dynamics), Bifurcation, Shear stress, Atherosclerosis